Research Project Database
Code: 1.18.03
1: 1.18.03
Title: Development and evaluation of a diagnostic tool for the detection of BoHV-1 during the acute phase.
2: Development and evaluation of a diagnostic tool for the detection of BoHV-1 during the acute phase.
Country: Switzerland
3: Switzerland
Funding Organisation: Federal Food Safety and Veterinary Office FSVO
4: Federal Food Safety and Veterinary Office FSVO
Animal Group:  
5:  
Pathogen:  
6:  
Disease:  
7:  
Category:  
8:  
9:  
Research Organisation: Institute of virology
University of Zurich (UZH)
10: Institute of virology
University of Zurich (UZH)
Number of Research Staff (FTE):  
11:  
Principal Investigator (PI):  
12:  
Cost (Euros): 104344
13: 104344
End Date (dd/mm/yyyy): 31-12-2019
14: 1577750400
Duration (months): 24
15: 24
Link:  
16:  
Project objectives and deliverables with estimated delivery dates for each deliverable (if possible): Bovine Herpesvirus typ 1 (BoHV-1) belongs to the subfamily of the Alphaherpesvirinae and is the causative agent of infectious bovine rhinotracheitis (IBR) and infectious pustular vulvovaginitis/balanopostthitis (IPV/IBP). The virus is able to establish a latent infection in the host upon a short acute phase. Serological tests for the detection of BoHV-1 are only useful after the reaction of the immune system but not during the acute infection. Therefore, a diagnostic tool for BoHV-1 during the acute phase based on isothermal amplification of viral DNA will be developed and evaluated. Various methods for the read out will be evaluated. Of note, the test procedure might be performed by technical staff in diagnostics laboratories with standard equipment. As no specialized equipment is necessary, the throughput of samples would be very high, which is an important factor in the event of an outbreak
17: Bovine Herpesvirus typ 1 (BoHV-1) belongs to the subfamily of the Alphaherpesvirinae and is the causative agent of infectious bovine rhinotracheitis (IBR) and infectious pustular vulvovaginitis/balanopostthitis (IPV/IBP). The virus is able to establish a latent infection in the host upon a short acute phase. Serological tests for the detection of BoHV-1 are only useful after the reaction of the immune system but not during the acute infection. Therefore, a diagnostic tool for BoHV-1 during the acute phase based on isothermal amplification of viral DNA will be developed and evaluated. Various methods for the read out will be evaluated. Of note, the test procedure might be performed by technical staff in diagnostics laboratories with standard equipment. As no specialized equipment is necessary, the throughput of samples would be very high, which is an important factor in the event of an outbreak
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