Research Project Database
| Code: | EMIDA25 |
| 1: | EMIDA25 |
| Title: | MOLTRAQ – Molecular tracing of viral pathogens in aquaculture |
| 2: | MOLTRAQ – Molecular tracing of viral pathogens in aquaculture |
| Country: | Denmark France Germany Norway |
| 3: | Denmark France Germany Norway |
| Funding Organisation: | French National Research Agency (ANR) The Ministry of Food, Agriculture and Fisheries of Denmark The Research Council of Norway Federal Ministry of Food Agriculture and Consumer Protection (BMELV) |
| 4: | French National Research Agency (ANR) The Ministry of Food, Agriculture and Fisheries of Denmark The Research Council of Norway Federal Ministry of Food Agriculture and Consumer Protection (BMELV) |
| Animal Group: | Fish Shellfish Crustaceans |
| 5: | Fish Shellfish Crustaceans |
| Pathogen: | Herpesviruses Nodaviruses Viral hemorrhagic septicemia virus (VHSV) Rhabdoviruses |
| 6: | Herpesviruses Nodaviruses Viral hemorrhagic septicemia virus (VHSV) Rhabdoviruses |
| Disease: | Viral haemorrhagic septicaemia (VHS) Infectious hematopoietic necrosis virus (IHNV) Koi herpes virus (KHV) disease |
| 7: | Viral haemorrhagic septicaemia (VHS) Infectious hematopoietic necrosis virus (IHNV) Koi herpes virus (KHV) disease |
| Category: | Epidemiology, Risk and Decision Support > Development, refinement, and evaluation of control strategies Epidemiology, Risk and Decision Support > Generic/Fundamental epidemiology and modelling Infection, immunity and biotechnology > Diagnostic test development, including microarray Infection, immunity and biotechnology > Fundamental/basic and Applied studies, including molecular, cellular, pathogen population dynamics and ecology > Host-Pathogen interactions (including immunomodulation and immune evasion) Infection, immunity and biotechnology > Fundamental/basic and Applied studies, including molecular, cellular, pathogen population dynamics and ecology > Molecular epidemiology Infection, immunity and biotechnology > Fundamental/basic and Applied studies, including molecular, cellular, pathogen population dynamics and ecology > Virology Infection, immunity and biotechnology > Generic capacity > Micro-organism collections |
| 8: | Development, refinement, and evaluation of control strategies Generic/Fundamental epidemiology and modelling Diagnostic test development, including microarray Host-Pathogen interactions (including immunomodulation and immune evasion) Molecular epidemiology Virology Micro-organism collections |
| 9: | 21,24,32,57,58,63,69 |
| Research Organisation: | National Veterinary Institute (DTU Vet) FLI - Friedrich Loeffler Institute National Veterinary Institute of Norway French Agency for Food, Environmental and Occupational Health & Safety (ANSES) French Research Institute for Exploitation of the Sea (IFREMER) Institut de recherche pour le développement (IRD) Norwegian Computing Center |
| 10: | National Veterinary Institute (DTU Vet) FLI - Friedrich Loeffler Institute National Veterinary Institute of Norway French Agency for Food, Environmental and Occupational Health & Safety (ANSES) French Research Institute for Exploitation of the Sea (IFREMER) Institut de recherche pour le développement (IRD) Norwegian Computing Center |
| Number of Research Staff (FTE): | |
| 11: | |
| Principal Investigator (PI): | Dr Edgar Brun, Norwegian Vetinerary Institute |
| 12: | Dr Edgar Brun, Norwegian Vetinerary Institute |
| Cost (Euros): | 1990198 |
| 13: | 1990198 |
| End Date (dd/mm/yyyy): | 31-03-2015 |
| 14: | 1427756400 |
| Duration (months): | 36 |
| 15: | 36 |
| Link: | |
| 16: | |
| Project objectives and deliverables with estimated delivery dates for each deliverable (if possible): | This project will i)generate and use spatio-temporal epidemiological data, phylogeographic data and gene expression data for important host-viral pathogen systems to identify important factors affecting the spread of diseases in aquaculture, and ii)integrate these in scenario simulation models to assess effects of various control strategies for selected host-pathogen systems. The purpose of the project is to increase knowledge on transmission, prevention and control of viral diseases in aquaculture and develop a generic approach to viral disease control by using information on epidemiological and physiogenetical attributes from several important aquatic animal viruses. The specific objectives are: 1)Collection of isolates of specific important aquatic animal viruses and their respective epidemiological data (from as wide host ranges, broad geographic distributions and variable pathogenicities as possible), 2)Characterisation of the isolates by phylogenetic and expression analyses and 3)Constructing scenario simulation models to assess effects of different control strategies. The project partners cover different fields of expertise and will contribute accordingly. NVI (NO) is the consortium coordinator of the project. NVI will be responsible for collecting surveillance data covering the incidence of viral infections in cultured populations in space and time and investigate the efficacy of disease intervention strategies. DTU-VET (DK) will primarily undertake research on VHSV and perch rhabdoviruses and include its large international strain collections for the project. DTU-Vet will expand the database www.fishpathogens.eu with the virus isolates included in the studies and create new sub databases for OsHV-1 and SAV isolates. ANSES (FR) has a large number of fish rhabdoviruses and various genotypes of nodaviruses, and will participate in the molecular characterization of yet uncharacterized or only partially characterized viruses. IFREMER (FR) has a collection of more than 100 samples infected with mollusc herpes-viruses, which will be used to investigate the genetic virus diversity. Bioinformatics will be applied to investigate the linkage between genomic features and virus properties. IRD (FR) has an extensive collection of KHV-isolates, which will be genotyped and included in the modelling methods. Furthermore, IRD will use own and other partner sequences to build DNA microarrays for expression studies. FLI (DE) will contribute with a large collection of IHNV, VHSV and KHV isolates. FLI will do comparative studies with regard to the origin, relationship and classification of the isolates. Additionally, FLI will work closely together with IRD in building microarrays. NR (NO) will incorporate data generated from the other partners into models that can exploit both traditional epidemiological data and genetic information on the disease agents, to simulate various disease spread intervention scenarios. |
| 17: | This project will i)generate and use spatio-temporal epidemiological data, phylogeographic data and gene expression data for important host-viral pathogen systems to identify important factors affecting the spread of diseases in aquaculture, and ii)integrate these in scenario simulation models to assess effects of various control strategies for selected host-pathogen systems. The purpose of the project is to increase knowledge on transmission, prevention and control of viral diseases in aquaculture and develop a generic approach to viral disease control by using information on epidemiological and physiogenetical attributes from several important aquatic animal viruses. The specific objectives are: 1)Collection of isolates of specific important aquatic animal viruses and their respective epidemiological data (from as wide host ranges, broad geographic distributions and variable pathogenicities as possible), 2)Characterisation of the isolates by phylogenetic and expression analyses and 3)Constructing scenario simulation models to assess effects of different control strategies. The project partners cover different fields of expertise and will contribute accordingly. NVI (NO) is the consortium coordinator of the project. NVI will be responsible for collecting surveillance data covering the incidence of viral infections in cultured populations in space and time and investigate the efficacy of disease intervention strategies. DTU-VET (DK) will primarily undertake research on VHSV and perch rhabdoviruses and include its large international strain collections for the project. DTU-Vet will expand the database www.fishpathogens.eu with the virus isolates included in the studies and create new sub databases for OsHV-1 and SAV isolates. ANSES (FR) has a large number of fish rhabdoviruses and various genotypes of nodaviruses, and will participate in the molecular characterization of yet uncharacterized or only partially characterized viruses. IFREMER (FR) has a collection of more than 100 samples infected with mollusc herpes-viruses, which will be used to investigate the genetic virus diversity. Bioinformatics will be applied to investigate the linkage between genomic features and virus properties. IRD (FR) has an extensive collection of KHV-isolates, which will be genotyped and included in the modelling methods. Furthermore, IRD will use own and other partner sequences to build DNA microarrays for expression studies. FLI (DE) will contribute with a large collection of IHNV, VHSV and KHV isolates. FLI will do comparative studies with regard to the origin, relationship and classification of the isolates. Additionally, FLI will work closely together with IRD in building microarrays. NR (NO) will incorporate data generated from the other partners into models that can exploit both traditional epidemiological data and genetic information on the disease agents, to simulate various disease spread intervention scenarios. |
| Files | No files are attached. |
